MK_RS5NF - Mouse kappa light chain, replacement and silent, 5-mer, non-functional targeting model.


5-mer model of somatic hypermutation targeting based on analysis of replacement and silent mutations in non-functional kappa light chain Ig sequences from NP-immunized Mus musculus.




TargetingModel object.


  1. Cui A, Di Niro R, Vander Heiden J, Briggs A, Adams K, Gilbert T, O’Connor K, Vigneault F, Shlomchik M and Kleinstein S (2016). A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data. The Journal of Immunology, 197(9), 3566-3574.

See also

See MK_RS1NF for the 1-mer substitution matrix from the same publication; HH_S5F for the human heavy chain silent 5-mer functional targeting model; HKL_S5F for the human light chain silent 5-mer functional targeting model; and U5N for the uniform 5-mer null targeting model.