MK_RS1NF - Mouse kappa chain, replacement and silent, 1-mer, non-functional substitution model.
1-mer substitution model of somatic hypermutation based on analysis of replacement and silent mutations in non-functional kappa light chain Ig sequences from NP-immunized Mus musculus.
A 4x4 matrix of nucleotide substitution rates. The rates are normalized, therefore each row sums up to 1.
M1NDistance from versions of SHazaM prior to 0.1.5.
- Cui A, Di Niro R, Vander Heiden J, Briggs A, Adams K, Gilbert T, O’Connor K, Vigneault F, Shlomchik M and Kleinstein S (2016). A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data. The Journal of Immunology, 197(9), 3566-3574.